Computational Bacterial Analytical ToolKit for Tuberculosis

Accessible M. tuberculosis bioinformatics to support research & public health

On GitHub


combatTB eXplorer

A comprehensive resource for M. tuberculosis genome, proteome and biochemical pathway knowledge.

Read more


An M. tuberculosis annotation Graph database used to represent interrelated knowledge and perform analysis.

Read more

combatTB Workbench

A customizable platform for variant discovery and annotation and phylogeny construction.

Read more


COMBAT-TB is a SAMRC Flagship and DST/NRF Research Chair funded project undertaken by researchers and software developers at SANBI that provides tools for understanding host-pathogen interactions. While this platform is targeted at Tuberculosis research, the goal is to deploy similar computational tools for other pathogens such as Listeriosis. Our focus is on two related software development initiatives:

COMBAT-TB eXplorer, a comprehensive knowledgebase of the M. tuberculosis genome and associated information.

COMBAT-TB Workbench, a set of tools and workflows for M. tuberculosis sequence data analysis.

The Team

(left to right, back row): Ziphozakhe Mashologu, Jamie Southgate, Thoba Lose, Peter van Heusden and Alan Christoffels
(left to right, front row): Farzaana Diedericks, Ruben Cloete, Tracey Calvert-Joshua, Mmakamohelo Direko and Lynley Abdoll






Get in touch


+27 21 959-3645


South African National Bioinformatics Institute
University of the Western Cape
Robert Sobukwe Road
Bellville, 7535
South Africa